IL-1ra antibody
882 €
In Stock
quantity
product details
Catalog number: 355 - 22895-100ul
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100ul
A23956
IL-1RA Rabbit mAb
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human COPA (P53621).
357.24 €
91-024
IL-1RA Recombinant Protein
Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family. Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases. It binds to IL-1 receptors in competition with IL-1, but does not elicit intracellular response from this binding. Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1RN.
691.15 €