IL-15 Antibody
765.98 €
In Stock
quantity
product details
Catalog number: 26 - 5172-100
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: each
70R-6175
Claudin 15 antibody
Rabbit polyclonal Claudin 15 antibody raised against the middle region of CLDN15
928.70 €
70R-7190
Tetraspanin 15 antibody
Rabbit polyclonal Tetraspanin 15 antibody raised against the C terminal of TSPAN15
928.70 €
7231-002mg
IL-15 Antibody
IL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.