Katalognummer: 223 - 11-312
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 0.1 mg
11-360
Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
ICS-M5259
Mouse ICOS (C137S, C138S) Protein, Fc Tag (ICS-M5259) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Leu 144 (Accession # Q9WVS0-1 (C137S, C138S)).
ICS-M52H8
Mouse ICOS (C137S, C138S) Protein, His Tag (ICS-M52H8) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Leu 144 (Accession # Q9WVS0-1 (C137S,C138S)).