Hydroxy Bosentan-d4
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Catalog number: 804 - HY-121385S1
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 1mg
HY-115417
Bosentan-d4
Bosentan-d4 is the deuterium labeled Bosentan. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
419.81 €
Hydroxy Bosentan-d4 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].