Human PAI-1
2408.22 €
2408.22 €
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product details
Catalog number: 544 - MBS691990-5x001mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 5x0.01mg
BT-AP06885-50ul
PAI-1 Polyclonal Antibody
SERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for SERPINE1.
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