Human KRAS (G12V) Protein, His Tag (active enzyme)
514.92 EUR
514.92 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - KRS-H5143
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 1mg
Parameters
| Additional information | KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) gene is a proto-oncogene that encodes a small GTPase transductor protein called KRAS. KRAS is also known as Ki-Ras, c-K-ras andc-Ki-ras. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation, promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. RAS is one of the most frequently mutated oncogenes in human cancer but the frequency and distribution of RAS gene mutations are not uniform. In details, mutation of glycine 12 (G12) causes RAS activation by interfering with GAP binding and GAP-stimulated GTP hydrolysis. The reference shows the pathway may as a potential therapy targets. |
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| Storage and shipping | -20℃ RT |
KRS-H5143
Human KRAS (G12V) Protein, His Tag (active enzyme)
Human KRAS (G12V) Protein, His Tag (KRS-H5143) is expressed from E. coli cells. It contains AA Thr 2 - Cys 185 (Accession # P01116-2 (G12V)).
514.92 €
KRS-H51H1
Human KRAS (G12A) Protein, His Tag (active enzyme)
Human KRAS (G12A) , His Tag (KRS-H51H1) is expressed from E. coli cells. It contains AA Thr 2 - Cys 185(G12A) (Accession # P01116-2 (G12A)).
2189.16 €
KRS-H51H1-100ug
Human KRAS (G12A) Protein, His Tag (active enzyme)
Human KRAS (G12A) , His Tag (KRS-H51H1) is expressed from E. coli cells. It contains AA Thr 2 - Cys 185(G12A) (Accession # P01116-2 (G12A)).
462.6 €
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