Human iPSC-derived Neural Progenitor Cells
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Catalog number: 566 - CSC-00861L
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: One Frozen vial
ABC-SC0059T
HighQC™ Human IPSC-Derived Neural Stem Cell-Alzheimer's Disease Patient (APOE4 HOM)
Gentaur Human iPSC-Derived Neural Stem Cells (NSCs) are derived from integration-free, induced pluripotent stem cells (iPSCs) under fully defined neural induction conditions. The NSCs express typical markers of cerebral cortical neural stem and progenitor cells such as PAX6, FOXG1 and nestin, and spontaneously form polarized neural tube-like rosette structures when plated as a monolayer in culture (see below). Additionally, Gentaur NSCs are capable of generating a spectrum of cerebral cortical excitatory and inhibitory neurons that are electrically active and have the ability to form functional synapses and circuits in vitro. After thawing and plating, the neural stem cells terminally differentiate to acquire mature electrophysiological properties, and form functional synaptic networks over a period of 40 ~ 50 days.Gentaur NSCs are easy to differentiate to neurons or mixed neural cell types, following our protocols and using our tailored media and reagent bundles. A highly pure population of neurons can be generated from Gentaur NSCs following the synchronous differentiation protocol. Using our specialized coating reagents, neurons derived from Gentaur NSCs can be maintained in culture long-term (andgt;1 year). NSCs are available from multiple donors to suit your research needs and have been characterized extensively.