Human IgG2 kappa Protein
720.21 €
720.21 €
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product details
Catalog number: 639 - abx060993-1mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 1 mg
96-413
IgG2 Fc Region Recombinant Protein
Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).