cyt-149

4-1BBL

Recombinant Human 4-1BB Ligand

390.00 €

100-001S

Human 4-1BBL Recombinant Protein

4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.

438.60 €

CD02405-5ug

Recombinant Human 4-1BBL protein

4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion, survival, and development of T cells. In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has been shown to interact with TRAF2. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain (ECD). The human 4-1BBL ECD shares 32 % and 35 % a.a. identity with Mouse and rat ECD.

418.40 €

A10202

4-1BBL/CD137L Rabbit pAb

432.84 €

A3386

4-1BBL/CD137L Rabbit mAb

Recombinant fusion protein containing a sequence corresponding to amino acids 363-656 of human MTHFR(NP_005948.3).

357.24 €

BS74411

4-1BBL/CD137L polyclonal antibody

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

358.00 €