HIF1A ELISA Kit (Mouse) (OKEH03021)

OKEH03021

HIF1A ELISA Kit (Mouse) (OKEH03021)

Description of target: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP300. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia.3 Publications;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39.8 pg/mL

1418.8 €

OKEH03021-96W

OKEH03021-96W - HIF1A ELISA Kit (Mouse)

982 €

STJ150026

Mouse HIF1A ELISA Kit

The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of HIF-1a in Mouse serum, plasma and other biological fluids

891.6 €

abx053660-5mg

Mouse Hypoxia Inducible Factor 1 Alpha (HIF1a) ELISA Kit

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DLR-HIF1a-Mu

Mouse Hypoxia Inducible Factor 1 Alpha (HIF1a) ELISA Kit

serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

798 €

DLR-HIF1a-Mu-48T

Mouse Hypoxia Inducible Factor 1 Alpha (HIF1a) ELISA Kit

A sandwich quantitative ELISA assay kit for detection of Mouse Hypoxia Inducible Factor 1 Alpha (HIF1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

1030.2 €