GITR / NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line
15566.63 €
In Stock
quantity
product details
Catalog number: 421 - 60546
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 2 vials
60651
NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line
NF-κB luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by 4 copies of NF-kB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.
3696.60 €
60621
NFAT Reporter (Luc) - Jurkat Cell Line
The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors.
3628.43 €
RC1042
NF-kB Luciferase Reporter-Jurkat Cell Line
The NF-kB Luciferase Reporter cell line is a stably transfected Jurkat T cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. NF-kB is a key transcription factor that is involved in immune and inflammatory responses, developmental processes, cellular growth and apoptosis. The NF-kB induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.
2976.67 €
RC1030
TLR8/NF-kB Luciferase Reporter-HEK293 Cell Line
The TLR8/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 8 (TLR8) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR8 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR8 ligand assay, in which upon activation by R848, TLR8 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
10077.78 €
RC1031
TLR9/NF-kB Luciferase Reporter-HEK293 Cell Line
The TLR9/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 9 (TLR9) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR9 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR9 ligand assay, in which upon activation by CpG, TLR9 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
10077.78 €
RC1039
TLR5/NF-kB Luciferase Reporter-HEK293 Cell Line
The TLR5/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 5 (TLR5) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR5 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR5 ligand assay, in which upon activation by Flagellin, TLR5 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).