GFB-8438
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product details
Catalog number: 639 - abx283454-100g
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 100 µg
HY-133012
GFB-8438
GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model[1].