Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery[2].