CRM197 is a genetically detoxified diphtheria toxin. It is expressed as a soluble, correctly folded ~58kDa recombinant protein in the cytoplasm of E. coli and then produced to >99% purity.
CRM197 is a genetically detoxified diphtheria toxin. It is expressed as a soluble, correctly folded ~58kDa recombinant protein in the cytoplasm of E. coli and then produced to >99% purity.
HC Toxin is a reversible, cell-permeable inhibitor of HDACs. It is a cyclic tetrapeptide first isolated from C. carbonum, a maize pathogen. It up-regulates the expression of 15-lipoxygenase-1 in colorectal cancer cells and has been shown to induce fetal hemoglobin in human primary erythroid cells.