Deg-1
1508.53 €
1508.53 €
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Catalog number: 804 - HY-153665
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10 mg
ABC-TC214S
B104-1-1
Tissue: embryo; Transfected with EcoR1 digested DNA from the rat neuroblastoma B104; Original line: NIH/3T3. The cells contain the transforming gene neu which induces synthesis of a tumor antigen of relative molecular mass 185, 000 (p185), strongly associated with the presence of neuro/glioblastoma oncogenes. The neu oncogene bears homology to erb-B and the tumor antigen p185 is serologically related to the epidermal growth factor receptor.
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Deg-1 is a a bifunctional probe with a cleavage group and a covalent binding group. Deg-1 covalently binds to the target nucleic acid, and serves as click-degrader to cleave a nucleic acid molecule. Deg-1 has potential to selectively cleave target nucleic acids in cells[1].