Compound 147 (AA147)
0.01 €Ask for quotation
0.01 €Ask for quotation
On request
quantity
product details
Catalog number: 639 - abx283245-100g
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 100 µg
HY-124293
AA147
AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection[1][2][3][4].
584.49 €