CM-272
1311.77 €
1311.77 €
In Stock
quantity
product details
Catalog number: 804 - HY-101925
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10 mg
A8745-25
CM-272
CM-272 is a first-in-class reversible dual inhibitor against G9a and DNMTs with IC50 values of 8 nM and 382 nM, respectively [1].G9a is a histone methyltransferase that is overexpressed in many tumors.
1534.59 €
A8745-5
CM-272
CM-272 is a first-in-class reversible dual inhibitor against G9a and DNMTs with IC50 values of 8 nM and 382 nM, respectively [1].G9a is a histone methyltransferase that is overexpressed in many tumors.
537.12 €
CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1].