CDK8-IN-13
506.56 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 804 - HY-149974
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10 mg
Parameters
| Storage and shipping | -20°C, 3 years; 4°C, 2 years (Powder) |
|---|
HY-149974
CDK8-IN-13
CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces Apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity[1].
506.56 €
HY-148561
CDK8-IN-12
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. CDK8-IN-12 has off-target kinase inhibition on GSK-3α, GSK-3β, PCK-θ with Kis of 13 nM, 4 nM, 109 nM, respectively. CDK8-IN-12 shows potent anti-proliferative effects selectively on MV4-11 cell. CDK8-IN-12 is an anti-cancer agent[1].
241.63 €
HY-151371
CDK8-IN-10
CDK8-IN-10 (compound 2) is a potent, selective cyclin-dependent kinase (CDK8) inhibitor with an IC50 value of 8.25 nM. CDK8-IN-10 can be used for research of cancer[1].
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