B2085-10
CCG-50014 is a potent and small molecule RGS inhibitor (IC50= 30 nM for RGS4, more than 20 fold selectivity for RGS4 over other RGS proteins). It is a GTPase activating protein that binds to the G? ?subunits of activated heterotrimeric G-proteins and boost GTP hydrolysis rate.
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