Caspase 9 Cleaved-Asp353 (CASP9 Cleaved-D353) Antibody
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Catalog number: 639 - abx330233-100g
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100 µg
BT-AP01905-20ul
Cleaved-Caspase-9 (D353) Polyclonal Antibody
CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
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BT-AP01905-50ul
Cleaved-Caspase-9 (D353) Polyclonal Antibody
CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
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ABP50009-003ml
Cleaved-Caspase-9 (D353) Polyclonal Antibody
A polyclonal antibody for detection of Cleaved-Caspase-9 D353) from Mouse, Rat. This Cleaved-Caspase-9 D353) antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-9 at AA range: 280-360