T6321

Stable INPP4A Expressing Raji Cell Line

6041.00 €

78071

Cas9-Expressing Raji cell pool

Cas9 (Streptococcus pyogenes CRISPR associated protein 9) is an endonuclease enzyme that, when recruited to a specific DNA sequence by the sgRNA (single guide RNA), introduces a double stranded break into the DNA. This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the targeted gene. Cas9-expressing Raji cells can be transduced or electroporated with sgRNA targeting a gene of interest to quickly generate knock-out cell pools or cell lines.

1342.50 €

CL-0189

Raji Cell Line

Homo sapiens, Human

38138.00 €

T3263

Cas9 Expressing HCT116 Cell Line

1308.50 €

T3203

CRE Expressing 293 Cell Line

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T3268

Cas9 Expressing Ovcar3 Cell Line

1308.50 €