![Anti-Thymidine Phosphorylase Antibody [A1A10]](/images/no-image-product-box.jpg "Anti-Thymidine Phosphorylase Antibody [A1A10]")
Anti-Thymidine Phosphorylase Antibody [A1A10]
465 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 992 - EM1901-22
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ul
Parameters
| Additional information | Recombinant protein within Human Thymidine Phosphorylase aa 19-239 / 482. |
|---|---|
| Storage and shipping | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
EM1901-22
Anti-Thymidine Phosphorylase Antibody [A1A10]
Platelet-derived endothelial cell growth factor (PD-ECGF), which is alternatively designated thymidine phosphorylase or gliostatin, is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Biologically active PD-ECGF is a functional dimer that consists of two single polypeptide chains that are expressed in platelets, placenta, foreskin fibroblasts and various squamous cell carcinomas, and they are slowly secreted from the cells. In addition, PD-ECGF is overexpressed in tumor and lesional psoriatic skin and lesional epidermis, indicating that it may play a role in the pathophysiology of psoriasis. Serine residues of PD-ECGF are frequently associated with nucleotide triphosphates, including ATP. In an ATP dependent manner, PD-ECGF is also able to catalyze the reversible phosphorolysis of thymidine to thymine, as it contains thymidine phosphorylase activities.
465 €
ET1702-31
Anti-Thymidine Kinase 1 Antibody [JF0970]
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.
496.5 €
YLD7731-100ul
Rabbit anti-Thymidine Kinase 1 Antibody
Rabbit polyclonal antibody to Thymidine Kinase 1
32 €
YLD7731-50ul
Rabbit anti-Thymidine Kinase 1 Antibody
Rabbit polyclonal antibody to Thymidine Kinase 1
32 €
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