anti- MACC1 antibody
1149.13 €
In Stock
quantity
product details
Catalog number: 710 - FNab04920
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100µg
5197-002mg
MACC1 Antibody
MACC1 Antibody: Metastasis associated in colon cancer 1 (MACC1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. MACC1 protein consists of four domains: ZU5, SH3, and two C-terminal death domains (DD). Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas. MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age, sex, tumor infiltration, nodal status, and lymph vessel invasion. Besides its involvement in signal transduction with the MET receptor, MACC1 also links MET signaling and apoptosis. MACC1 may also be an important therapeutic target for colorectal cancer treatment.
443.66 €
ABP53023-01ml
MACC1 Polyclonal Antibody
A polyclonal antibody for detection of MACC1 from Human, Mouse. This MACC1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human MACC1
707.20 €
ABP53023-02ml
MACC1 Polyclonal Antibody
A polyclonal antibody for detection of MACC1 from Human, Mouse. This MACC1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human MACC1
934.45 €