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Anti-Human IL-17B Antibody

Anti-Human IL-17B Antibody
Anti-Human IL-17B Antibody

Anti-Human IL-17B Antibody

755.99 €

755.99 €
In Stock
quantity
product details

Catalog number: 209 - 101-M485

Product Category: Business & Industrial > Science & Laboratory

Supplier:

ReliaTechGentaur

Size: 100 µg

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The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.