Anti-CXCR4 Antibody
823.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 519 - A00031-1
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.1mg
Parameters
| Additional information | WB: 1 - 2 μg/mL; IP/ ICC: 2 μg/mL; IHC-P: 5 μg/mL; IF: 20 μg/mL; Flow Cyt: 0.1 μg/mL. ;Antibody validated: Western Blot in human, mouse, and rat samples; Immunohistochemistry, Immunocytochemistry and Immunofluorescence in human samples; Flow Cytometry in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
|---|---|
| Storage and shipping | CXCR4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
A00031-1
Anti-CXCR4 Antibody
Boster Bio Anti-CXCR4 Antibody (Catalog # A00031-1). Tested in ELISA, WB, ICC, IP, IF, Flow Cytometry, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
823.5 €
ER1802-28
Anti-CXCR4 Antibody
The C-X-C or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemo-attractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB and CXCR-4 (also known as LESTR or fusin). CXCR-4 is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. CXCR-4 has been identified as the major co-receptor for T-tropic HIV-1 and SDF-1 has been shown to inhibit HIV-1 infection.
433.5 €
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