C-Reactive Protein (CRP) is an annular, pentameric protein found in blood plasma. CRP belongs to the beta-globulin family of plasma proteins and its name is derived from the ability to precipitate a group C polysaccharide of pneumococcus in the presence of Ca2+. Serum levels of CRP are elevated in a wide variety of acute and chronic inflammatory conditions. These conditions include most bacterial and some viral infections, rheumatic fever, rheumatoid arthritis, and many collagen diseases. CRP serum levels are also valuable in detection and evaluation of tissue injury, acute myocardial infarction, transplant rejection, and several malignant disorders.