Anti-Aurora B Antibody [SC55-08]

ET1610-25

Anti-Aurora B Antibody [SC55-08]

Aurora related kinase-1 (ARK-1, STK15, Aurora2, Aik1) and -2 (ARK-2, STK12, Aurora1) are centrosome-associated serine/ threonine kinases that regulate centrosome separation, bipolar spindle assembly, and chromosome segregation during mitosis. ARK-1 and -2 are expressed in the nucleus and localize to distinct portions of mitotic machinery such as the centrosome, spindle poles (ARK-1), and midbody (ARK-2) during mitosis. ARK-1 and -2 transcripts are present at high levels in human thymus and fetal liver. ARK-1 protein has elevated expression in colon carcinoma lines (HT-29, SNU-C2B, COLO 205, SW480, 837 and 948) and accumulates during metaphase in HeLa cells. ARK-2 protein levels are maximal during both S and G2/M phases, whereas ARK-1 protein is degraded after G2/M via the ubiquitin-proteasome pathway. ARK-2 has a unique genetic loci relative to ARK-1, suggesting that these two kinases, with oncogenic potential, have different roles in cell cycle progression.

496.5 €

M00762-4

Anti-Aurora-B (AURKB) Rabbit Monoclonal Antibody, Clone#RM278

Boster Bio Anti-Aurora-B (AURKB) Rabbit Monoclonal Antibody, Clone#RM278 (Catalog # M00762-4). Tested in IHC, WB applications. This antibody reacts with Human.

796.5 €

39233

Anti-Aurora B Antibody

898.5 €

1759-20uL

Anti-Aurora kinase B Rabbit Monoclonal Antibody

423.5 €

YF-MA10893

Anti-Aurora A (5F8)

Mouse monoclonal to Aurora A

803.4 €

STJ500191

Anti-Aurora A Antibody FITC

1204.8 €