Catalog number: 796 - AF4629-50ul
Product Category: Business & Industrial > Science & Laboratory
Size: 50ul
70R-1171
Rabbit polyclonal alpha Actinin 4 antibody raised against the N terminal of ACTN4
70R-13518
Affinity purified Rabbit polyclonal alpha Actinin 4 antibody
BT-MCA0137-100ul
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.