AG14361
472.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 940 - 401020
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 1.0mg
Parameters
| Additional information | Smiles Code: O=C1C2=C3C(N=C(C4=CC=C(CN(C)C)C=C4)N3CCN1)=CC=C2 |
|---|
HY-12032
AG14361
AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50s are 29 nM and 14 nM, respectively.
1394.89 €
27602-1
AG-14361
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy. AG14361 enhances the growth-inhibitory and cytotoxic effects of topoisomerase I poisons and increases the persistence of camptothecin-induced DNA single-strand breaks.
457.5 €
27602-2
AG-14361
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy. AG14361 enhances the growth-inhibitory and cytotoxic effects of topoisomerase I poisons and increases the persistence of camptothecin-induced DNA single-strand breaks.
690 €
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